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<i>Schisandra lancifolia<_i> (Rehd. et Wils.) A. C. Smith

" in MedChemExpress (MCE) Product Catalog:

49

Inhibitors & Agonists

38

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0860

    Schizantherin-E

    Others Inflammation/Immunology
    Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.
    Schisantherin E
  • HY-N11939

    HIV Infection
    Kadsuralignan A (compound 1) is a dibenzocyclooctadiene lignan isolated from the leaves and stems of Schisandra lancifolia. Kadsuralignan A has anti-HIV activity with EC50=2.23 μg/mL .
    Kadsuralignan A
  • HY-N10030

    Others Others
    11-O-Syringylbergenin is a bergenin derivative isolated from the whole plants of Corylopsis willmottiae Rehd. et Wils
    11-O-Syringylbergenin
  • HY-N11944

    Others Others
    Schiarisanrin E (compound 5) is a lignan that can be isolated from Schisandra chinensis .
    Schiarisanrin E
  • HY-N3512

    Others Cancer
    Wilfornine A is a natural product that can be isolated from Schisandra sphenanthera. Wilfornine A has anti-tumor effect .
    Wilfornine A
  • HY-N2870

    SchisanWilsonin N

    Others Others
    Angeloylisogomisin O is a compound isolated from the aerial parts of Schisandra propinqua var. propinqua .
    Angeloylisogomisin O
  • HY-N6048

    HIV Infection
    Lancifodilactone F (compound 1) can be isolated from the leaves and stems of Schisandra lancifolia. Lancifodilactone F has anti-HIV activity with EC50=20.69 μg/mL. Lancifodilactone F has cytotoxicity against C8166 cells (CC50 >200 μg/mL) .
    Lancifodilactone F
  • HY-N11172

    Others Neurological Disease
    Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .
    Schibitubin I
  • HY-145889

    Others Others
    LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL * and WIL-FL * T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer .
    LC kinetic stabilizer-1
  • HY-N0691
    Schisandrin
    2 Publications Verification

    Schizandrin; Schizandrol; Schizandrol-A

    Autophagy Inflammation/Immunology Cancer
    Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .
    Schisandrin
  • HY-N12065

    Others Others
    Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis .
    Parisyunnanoside H
  • HY-N3832

    (-)-Epinortrachelogenin

    Others Others
    Epinortrachelogenin ((-)-Epinortrachelogenin) is a natural lignan found in the plateau medicinal plant Daphne acutiloba Rehd .
    Epinortrachelogenin
  • HY-113435

    Endogenous Metabolite Metabolic Disease
    8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS).
    8-Dehydrocholesterol
  • HY-122969

    Others Cancer
    Anwuweizonic acid is a natural compound, isolated from Schisandra propinqua. Anwuweizonic acid is the putative anticancer active principle of Schisandra propinqua .
    Anwuweizonic acid
  • HY-N12046

    HIV Infection Inflammation/Immunology Cancer
    Schineolignin B is a Lignan that can be isolated from the fruit of schisandra chinensis. schisandra chinensis has antihepatitis, antitumor, and anti-HIV-1 activities .
    Schineolignin B
  • HY-N12047

    HIV Infection Inflammation/Immunology Cancer
    Schineolignin C is a Lignan that can be isolated from the fruit of schisandra chinensis. schisandra chinensis has antihepatitis, antitumor, and anti-HIV-1 activities .
    Schineolignin C
  • HY-N12425

    Others Others
    Heteroclitin A is a lignan isolated from the stems of Schisandra propinqua.
    Heteroclitin A
  • HY-N2222

    Epigomisin O is isolate from the fruits of Schisandra plants .
    Epigomisin O
  • HY-N5044

    Arisanschinin L

    Others Others
    Schisanwilsonin B is a lignan from the fruits of Schisandra wilsoniana .
    Schisanwilsonin B
  • HY-N10805

    Others Others
    Schisanlignone C is a chemical component of Schisandra viridis a. c. sm .
    Schisanlignone C
  • HY-N10806

    Others Others
    Schisanlignone D is a chemical component of Schisandra viridis a. c. sm .
    Schisanlignone D
  • HY-N11936

    Others Others
    Rubriflorin B is a lignan that can be isolated from Schisandra rubriflora .
    Rubriflorin B
  • HY-N12048

    Others Others
    Schisandrathera D is a lignan that can be isolated from Schisandra sphenanthera .
    Schisandrathera D
  • HY-N11947

    Others Others
    Schisanligone B is a lignan isolated from Schisandra chinensis seeds .
    Schisanlignone B
  • HY-N2271
    Angeloylgomisin O
    1 Publications Verification

    Angeloylgomisin O, a lignin extract of Schisandra rubriflora. Anti-inflammatory properties .
    Angeloylgomisin O
  • HY-N2293

    Chamigrenal is a natural product that can be extract from the fruits of Schisandra sphenanthera .
    Chamigrenal
  • HY-N8622A

    Others Others
    Heteroclitin B is a saturated dibenzocyclooctene lignan isolated from the stems of Schisandra chinensis.
    Heteroclitin B
  • HY-N11917

    Others Others
    Schisantherin S is a dibenzocyclooctene-type lignan isolated from the stems of Schisandra chinensis (Kadsura) .
    Schisantherin S
  • HY-N11971

    Others Others
    Yunnankadsurin B is a dibenzocyclooctene-type lignan isolated from the stems of Schisandra chinensis (Kadsura) .
    Yunnankadsurin B
  • HY-N0859

    Schizanhenol; Gomisin-K3

    UGT Cancer
    Schisanhenol is a natural compound solated from Schisandra rubriflora; UGT2B7 UDP-glucuronosyltransferases inhibitor.
    Schisanhenol
  • HY-N1539

    19-epi-Arisanlactone D; 22-O-Acetylarisanlactone C; 24,25-Dihydropreschisanartanin

    Preschisanartanin B (compound 9) is a preschisanartane-type nortriterpenoid. Preschisanartanin B can be isolated from the Schisandra arisanensis .
    Preschisanartanin B
  • HY-N2209

    Angeloylgomisin H, as a major lignin extract of Schisandra rubriflora, has the potential to improve insulin-stimulated glucose uptake by activating PPAR-γ .
    Angeloylgomisin H
  • HY-N4100
    Trilobatin
    1 Publications Verification

    HIV SGLT Infection
    Trilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd , Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope . Neuroprotective effects . Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells .
    Trilobatin
  • HY-N8260

    Others Neurological Disease
    Angeloylgomisin Q is a new dibenzocyclooctadiene lignan from the stems of Schisandra sphaerandra . Angeloylgomisin Q has the potential for alzheimer's disease research .
    Angeloylgomisin Q
  • HY-N0089
    Schisandrin B
    Maximum Cited Publications
    7 Publications Verification

    γ-Schisandrin; Wuweizisu B

    Autophagy Reactive Oxygen Species Neurological Disease Cancer
    Schisandrin B (γ-Schisandrin) is a biphenylcyclooctadiene derivative isolated from Schisandra chinensis and has been shown to have antioxidant effects on the liver and heart of rodents.
    Schisandrin B
  • HY-N2267

    (+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart .
    (+)-Schisandrin B
  • HY-N2270

    p38 MAPK ERK IKK Inflammation/Immunology
    Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity .
    Chicanine
  • HY-N2266

    Benzoylgomisin O isolated from Schisandra rubriflora, has inhibitory activity against 15-LOX, COX-1 and COX-2 enzymes and anti-inflammatory activity .
    Benzoylgomisin O
  • HY-N6866

    Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Gomisin N, isolated from Schisandra chinensis. Gomisin N has the potential for use in the treatment of allergy. Gomisin N is an anti-cancer agent candidate capable of inhibiting the proliferation and inducing the apoptosis in cancer .
    Gomisin N
  • HY-122935

    HIV Reverse Transcriptase Infection
    Nigranoic acid is a triterpenoid separated from Schisandra chinensis. Nigranoic acid inhibits HIV-1 reverse transcriptase. Nigranoic acid exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model .
    Nigranoic acid
  • HY-16911
    AFN-1252
    5+ Cited Publications

    API-1252; Debio 1452

    Bacterial Antibiotic Infection
    AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .
    AFN-1252
  • HY-N7543

    HIV Infection
    Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects .
    Schisantherin D
  • HY-N2413

    Others Metabolic Disease
    Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule .
    Gomisin D
  • HY-N2264

    Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu agent resistant virus strain) activities .
    Wulignan A1
  • HY-N3963

    (+)-Gomisin M2

    HIV Infection Neurological Disease Inflammation/Immunology Cancer
    Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research .
    Gomisin M2
  • HY-N0692
    Schisandrol B
    1 Publications Verification

    Gomisin-A; TJN-101; Wuweizi alcohol-B

    Reactive Oxygen Species Cytochrome P450 Autophagy Cancer
    Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities .
    Schisandrol B
  • HY-N2245

    Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera . Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia .
    Schisandrone
  • HY-N0385
    Gomisin J
    3 Publications Verification

    AMPK Calcium Channel Cardiovascular Disease Metabolic Disease
    Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity . Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca 2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease .
    Gomisin J
  • HY-N2896

    Reactive Oxygen Species Inflammation/Immunology
    Arjunolic acid is a saponin isolated from Cyclocarya paliurus and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potent antioxidant and plays an important role in the protection of cells and tissues against deleterious effects of reactive oxygen species .
    Arjunolic acid

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